IPCS INCHEM Home
TRICHLORPHON
ICSC: 0585
Peer-Review Status: 10.08.1997 Validated
Dimethyl-2,2,2-trichloro-1-hydroxyethylphosphonate
Trichlorphene
(2,2,2-Trichloro-1-hydroxyethyl) phosphonic acid dimethyl ester
Chlorofos 
CAS #: 52-68-6 RTECS #: TA0700000
UN #: 2783
EC #: 015-021-00-0
EINECS #: 200-149-3
    Formula: C4H8Cl3O4P
Molecular mass: 257.4

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION      
 
EXPOSURE   PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF (PREGNANT) WOMEN! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Sweating. Nausea. Vomiting. Dizziness. Pupillary constriction, muscle cramp, excessive salivation. Laboured breathing. Convulsions. Unconciousness. Symptoms may be delayed. See Notes.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! See Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain. Pupillary constriction. Blurred vision.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Nausea. Vomiting. Weakness. Abdominal cramps. Diarrhoea. Pupillary constriction. Muscle cramps. Excessive salivation. Laboured breathing. Unconsciousness.  Do not eat, drink, or smoke during work.  Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Do NOT wash away into sewer. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: Xn, N; R: 22-43-50/53; S: (2)-24-37-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT7-III.  Separated from strong bases and food and feedstuffs. Keep in a well-ventilated room. 

IMPORTANT DATA
Physical State; Appearance
WHITE CRYSTALS. 

Physical dangers
 

Chemical dangers
Decomposes on heating and on contact with acids and bases. This produces toxic fumes. Attacks many metals. 

Occupational exposure limits
TLV (inhalable fraction): 1mg/m³ as TWA; A4 (not classifiable as a human carcinogen); BEI issued; (ACGIH 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. 

Effects of short-term exposure
The substance may cause effects on the nervous system by a cholinesterase inhibiting effect. This may result in convulsions, respiratory failure and death. Cholinesterase inhibition. Exposure at high levels could cause death. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the nervous system. Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Melting point: 83-84°C
Relative density (water = 1): 1.73
Solubility in water, g/100ml at 25°C: 15.4
Vapour pressure, Pa at 20°C: <0.01
Octanol/water partition coefficient as log Pow: 0.48  
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to bees and fish. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
The symptoms of acute intoxication do not become manifest until some hours have passed.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
The recommendations on this card apply to the pure form.
Commercial formulations are often mixtures including impurities, solvent or other agents which modify toxic and physicochemical properties.
Acrol, DEP, DANEX, DIMETOX are trade names.
Card has been partly updated in October 2004 and 2005.
See sections Occupational Exposure Limits, EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations