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beta-PROPIOLACTONEICSC: 0555
1,3-Propiolactone
2-Oxetanone
Propanolide
April 2017
CAS #: 57-57-8
UN #: 2810
EC Number: 200-340-1

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible.  Above 74°C explosive vapour/air mixtures may be formed.  NO open flames.  Above 74°C use a closed system and ventilation.  Use water spray, powder, alcohol-resistant foam, carbon dioxide.  In case of fire: keep drums, etc., cool by spraying with water. 

 AVOID ALL CONTACT!  
  SYMPTOMS PREVENTION FIRST AID
Inhalation Burning sensation. Cough. Sore throat. Headache. Nausea. Shortness of breath. Vomiting.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer immediately for medical attention. 
Skin Redness.  Protective gloves. Protective clothing.  Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain. Burns.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Give one or two glasses of water to drink. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: self-contained breathing apparatus. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

skull;toxiccancer;health haz
DANGER
Combustible liquid
Fatal if inhaled
Causes skin irritation
Causes serious eye irritation
May cause cancer
May cause respiratory irritation 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: I 

STORAGE
Separated from food and feedstuffs. Cooled. Well closed. Ventilation along the floor. 
PACKAGING
Do not transport with food and feedstuffs. 
beta-PROPIOLACTONE ICSC: 0555
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH PUNGENT ODOUR. 

Physical dangers
 

Chemical dangers
The substance may polymerize due to warming. This generates fire or explosion hazard. 

Formula: C3H4O2
Molecular mass: 72.1
Decomposes at 162°C
Melting point: -33.4°C
Density (at 20°C): 1.1 g/ml
Solubility in water, g/100ml at 25°C: 37 (good)
Vapour pressure, Pa at 25°C: 453
Flash point: 74°C c.c.
Explosive limits, vol% in air: 2.9-?
Octanol/water partition coefficient as log Pow: 0.46 (estimated)
Relative vapour density (air = 1): 2.5 (calculated)
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.0 


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion. 

Effects of short-term exposure
The substance is severely irritating to the eyes. The substance is irritating to the skin and respiratory tract. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C on spraying. 

Effects of long-term or repeated exposure
This substance is probably carcinogenic to humans. 


OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.5 ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans).
MAK: skin absorption (H); carcinogen category: 2 

ENVIRONMENT
Environmental effects from the substance have not been investigated adequately. 

NOTES
 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T+; R: 45-26-36/38; S: 53-45; Note: E 

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    See Also:
       Toxicological Abbreviations