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HEXACHLOROCYCLOHEXANE (MIXED ISOMERS)
ICSC: 0487
Peer-Review Status: 25.11.2009 Validated
1,2,3,4,5,6-Hexachlorocyclohexane (mixed isomers)
BHC/HCH (mixture of isomers)
1,2,3,4,5,6-Benzenehexachloride (mixed isomers) 
CAS #: 608-73-1 RTECS #: GV3150000
UN #: 2761
EC #: 602-042-00-0
EINECS #: 210-168-9
    Formula: C6H6Cl6 / ClCH(CHCl)4CHCl
Molecular mass: 290.8

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Not combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION Risk of fire and explosion if formulations contain flammable/explosive solvents.    In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT! AVOID EXPOSURE OF BREASTFEEDING WOMEN!   
Inhalation Cough. Sore throat. Further see Ingestion.  Avoid inhalation of dust.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED!  Protective gloves. Protective clothing.  Wear protective gloves when administering first aid. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness.  Wear face shield or eye protection in combination with breathing protection if powder.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Headache. Nausea. Vomiting. Diarrhoea. Dizziness. Tremor. Convulsions.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give a slurry of activated charcoal in water to drink, but NOT if convulsions occur. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance, chemical protection suit including self-contained breathing apparatus and protective gloves. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable non-metallic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT wash away into sewer.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 21-25-40-50/53; S: (1/2)-22-36/37-45-60-61; Note: C 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
Signal: Danger
Toxic if swallowed
Harmful in contact with skin
Suspected of causing cancer
May cause harm to breast-fed children
Causes damage to central nervous system
May cause damage to nervous system, bone marrow, kidneys and liver through prolonged or repeated exposure
Very toxic to aquatic life with long lasting effects 
skull;toxiccancer;health hazenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
  Well closed. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. Separated from bases, metals and food and feedstuffs. 

IMPORTANT DATA
Physical State; Appearance
WHITE TO BROWNISH FLAKES OR WHITE CRYSTALLINE POWDER, WITH CHARACTERISTIC ODOUR. 

Physical dangers
No data. 

Chemical dangers
Decomposes on contact with hot surfaces or flames. This produces toxic and corrosive fumes including chlorine (see ICSC 0126), hydrogen chloride (see ICSC 0163) and phosgene (see ICSC 0007). Reacts with bases and powdered metals. 

Occupational exposure limits
TLV not established.
MAK (inhalable fraction): 0.5 mg/m³; Peak limitation category: II(8); Skin absorption (H); (DFG 2009). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed. 

Effects of short-term exposure
The substance may cause effects on the central nervous system. The effects may be delayed. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the nervous system, bone marrow, kidneys and liver. This substance is possibly carcinogenic to humans. Animal tests show that this substance possibly causes toxic effects upon human reproduction. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: see Notes
Melting point: see Notes
Density: 1.9 g/cm³
Solubility in water: very poor
Vapour pressure, kPa at 20°C: see Notes  
The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur along the food chain, for example in fish and seafood. The substance may cause long-term effects in the aquatic environment. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Boiling point, melting point and vapour pressure are depending on isomeric composition.
Depending on the degree of exposure, periodic medical examination is suggested.
The symptoms of convulsions do not become manifest until 0.5 to several hours.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Do NOT take working clothes home.
Do NOT use in the vicinity of a fire or a hot surface, or during welding.
Occupational Exposure Limits : MAK value is for technical mixture of alpha and beta isomers (0.5 mg/m3=(Conc.alpha-HCH divided by 5) + Conc beta-HCH).
See also ICSC #0053 Lindane, #0487 Hexachlorocyclohexane (mixed isomers), #0795 alpha-Hexachlorocyclohexane, #0796 beta-Hexachlorocyclohexane. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Hexachlorocyclohexane (Mixed Isomers) (PIM 257)