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2-METHOXYETHYL ACETATE
ICSC: 0476
Peer-Review Status: 26.11.2003 Validated
Ethylene glycol monomethyl ether acetate
2-Methoxyethanol acetate
Acetic acid, 2-methoxyethyl ester
Methyl cellosolve acetate
Methyl glycol acetate 
CAS #: 110-49-6 RTECS #: KL5950000
UN #: 1189
EC #: 607-036-00-1
EINECS #: 203-772-9
    Formula: C5H10O3 / CH3COOCH2CH2OCH3
Molecular mass: 118.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable.  NO open flames, NO sparks and NO smoking.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Above 45°C explosive vapour/air mixtures may be formed.  Above 45°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT!   
Inhalation Dizziness. Drowsiness. Headache.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Dry skin. Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Nausea. Vomiting. Weakness. Unconsciousness. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.   
EC Classification
Symbol: T; R: 60-61-20/21/22; S: 53-45; Note: E 
UN Classification
UN Hazard Class: 3; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30GF1-III.
NFPA Code: H1; F2; R. 
Fireproof. Separated from strong oxidants, strong bases and strong acids. Keep in the dark. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
The substance can presumably form explosive peroxides. Reacts with strong oxidants and strong bases. 

Occupational exposure limits
TLV: 0.1ppm as TWA; (skin); (ACGIH 2007).
MAK: 1 ppm, 4.9 mg/m³; Peak limitation category: II(8); Pregnancy risk group: B; Skin absorption (H); (DFG 2008). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The vapour is mildly irritating to the eyes. The substance may cause effects on the bone marrow and central nervous system. The substance may cause effects on the blood at high levels. This may result in lesions of blood cells and kidney impairment. Exposure far above the OEL could cause unconsciousness. 

Effects of long-term or repeated exposure
The liquid defats the skin. The substance may have effects on the bone marrow and blood. This may result in lesions of blood cells and kidney impairment. May cause toxicity to human reproduction or development. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 145°C
Melting point: -65°C
Relative density (water = 1): 1.01
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 0.27
Relative vapour density (air = 1): 4.1
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 45°C c.c.
Auto-ignition temperature: 380°C
Explosive limits, vol% in air: 1.5 (at 93°C) - 12.3 (at 93°C)
Octanol/water partition coefficient as log Pow: 0.121  
The substance is harmful to aquatic organisms. 

NOTES
Check for peroxides prior to distillation; eliminate if found.
Health effects of exposure to the substance have not been investigated adequately.
Its effects are deduced from those of similar substances.
Card has been partially updated in July 2007: see Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations