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DIETHYLTHIOPHOSPHORYL CHLORIDE
ICSC: 0448
Peer-Review Status: 27.03.1996 Validated
Phosphorochloridothioic acid O,O-diethyl ester
Diethyl chlorothiophosphate
Diethyl phosphochloridothionate 
CAS #: 2524-04-1 RTECS #: TD1780000
UN #: 2751
EINECS #: 219-755-4
    Formula: C4H10ClO2PS
Molecular mass: 188.6

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames. NO contact with hot surfaces.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION     In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water. 
 
EXPOSURE   PREVENT GENERATION OF MISTS!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Burning sensation. Cough. Shortness of breath. Sore throat. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Burning sensation. Pain. Blisters. Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes MAY BE ABSORBED! Redness. Pain. Blurred vision. Loss of vision. Severe deep burns.  Wear safety goggles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal cramps. Burning sensation. Diarrhoea. Vomiting. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Rest. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
 
UN Classification
UN Hazard Class: 8; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-864.  Separated from food and feedstuffs. Dry. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on contact with water. This produces hydrogen chloride. Upon heating, toxic fumes are formed. Decomposes on heating. This produces toxic fumes. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C. 

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Inhalation of of the vapour may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: >110°C
Melting point: <-75°C
Relative density (water = 1): 1.19
Solubility in water: reaction
Vapour pressure, Pa at 50°C: 190
Flash point: 92°C c.c. 
This substance may be hazardous to the environment. Special attention should be given to water quality. 

NOTES
This ICSC does NOT cover commercial formulations!
Please consult the manufacturer for proper information.
Depending on the degree of exposure, periodic medical examination is indicated.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Do NOT take working clothes home.
Also consult ICSC # 0163 Hydrogen chloride. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations