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BROMOCHLOROMETHANE
ICSC: 0392
Peer-Review Status: 12.4.2013 Validated
Chlorobromomethane
Methylene chlorobromide 
CAS #: 74-97-5 RTECS #: PA5250000
UN #: 1887
EINECS #: 200-826-3
    Formula: CH2BrCl
Molecular mass: 129.4

TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.  See Chemical Dangers.  In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION Heating will cause rise in pressure with risk of bursting.  See Chemical Dangers  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   PREVENT GENERATION OF MISTS!   
Inhalation Sore throat. Cough. Nausea. Headache. Shortness of breath. Dizziness. Drowsiness. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Administration of oxygen may be needed. Artificial respiration may be needed. Refer for medical attention. 
Skin Dry skin. Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety goggles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
Signal: Warning
Harmful if inhaled
Causes skin and eye irritation
May cause respiratory irritation
May cause damage to central nervous system and blood
May cause drowsiness or dizziness
May be harmful if swallowed and enters airways 
excl mark;warncancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
  Separated from food and feedstuffs, strong oxidizers, strong bases and metals. Ventilation along the floor. Do NOT store or transport in containers made from aluminium or plastic. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-YELLOW LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air. 

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including hydrogen chloride, phosgene and hydrogen bromide. Reacts violently with strong oxidants, strong bases and metals such as sodium, potassium, magnesium and powdered aluminium. This generates fire and explosion hazard. Attacks some forms of rubber, plastics and coatings. 

Occupational exposure limits
TLV: 200ppm as TWA; (ACGIH 2012).
MAK: Carcinogen category: 3B; Skin absorption (H); (DFG 2012). 

Routes of exposure
The substance can be absorbed into the body by inhalation, by ingestion and through the skin. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The vapour is irritating to the eyes, skin and respiratory tract. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis. Inhalation of high concentrations of the vapour may cause lung oedema. See Notes. Exposure at high concentrations could cause lowering of consciousness. Exposure could cause carbon monoxide poisoning. This may result in impaired functions. The effects may be delayed. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the central nervous system and liver. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 68°C
Melting point: -88°C
Relative density (water = 1): 2.0
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.5
Solubility in water, g/100ml at 20°C: 0.9 (poor)
Vapour pressure, kPa at 20°C: 14.7
Relative vapour density (air = 1): 4.5
Octanol/water partition coefficient as log Pow: 1.41
Viscosity: 0.33 mm²/s at 20°C 
This substance may be hazardous to the environment. Special attention should be given to its impact on the ozone layer. 

NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations