IPCS INCHEM Home
ADIPIC ACID
ICSC: 0369
Peer-Review Status: 23.03.1998 Validated
Hexanedioic acid
1,4-Butanedicarboxylic acid 
CAS #: 124-04-9 RTECS #: AU8400000
EC #: 607-144-00-9
EINECS #: 204-673-3
    Formula: C6H10O4 / HOOC(CH2)4COOH
Molecular mass: 146.14

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION Finely dispersed particles form explosive mixtures in air.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent deposition of dust. Prevent build-up of electrostatic charges (e.g., by grounding).  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   PREVENT DISPERSION OF DUST! STRICT HYGIENE!   
Inhalation Cough. Sore throat.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin   Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion   Do not eat, drink, or smoke during work.  Rinse mouth. Rest. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Sweep spilled substance into covered plastic containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.   
EC Classification
Symbol: Xi; R: 36; S: (2) 
UN Classification
 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H; F1; R0.   

IMPORTANT DATA
Physical State; Appearance
ODOURLESS COLOURLESS CRYSTALLINE POWDER. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. If dry, it can be charged electrostatically by swirling, pneumatic transport, pouring, etc. 

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes of valeric acid and other substances. The substance is a weak acid. Reacts with oxidizing materials. 

Occupational exposure limits
TLV: 5mg/m³ as TWA; (ACGIH 1997). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. Inhalation of the aerosol may cause asthmatic reactions. See Notes. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 338°C
Melting point: 152°C
Density: 1.36 g/cm³
Solubility in water, g/100ml at 15°C: 1.4 (moderate)
Vapour pressure, Pa at 18.5°C: 10
Relative vapour density (air = 1): 5.04
Flash point: 196°C c.c.
Auto-ignition temperature: 422°C
Octanol/water partition coefficient as log Pow: 0.08  
 

NOTES
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Anyone who has shown symptoms of asthma due to this substance should avoid all further contact with this substance. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Adipic acid (FAO Nutrition Meetings Report Series 40abc)
       Adipic acid (WHO Food Additives Series 12)
       ADIPIC ACID (JECFA Evaluation)
       Adipic Acid (SIDS)