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DISODIUM ARSENATE HEPTAHYDRATE
ICSC: 0326
Peer-Review Status: 20.10.2005 Validated
Arsenic acid, disodium salt, heptahydrate
Sodium arsenate heptahydrate
Sodium arsenate, dibasic, heptahydrate 
CAS #: 10048-95-0 RTECS #: CG0900000
UN #: 1685
EC #: 033-005-00-1
    Formula: Na2HAsO4. 7H2O
Molecular mass: 312.0

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION Risk of fire and explosion on contact with metals. See Chemical Dangers.     
 
EXPOSURE   PREVENT DISPERSION OF DUST! AVOID ALL CONTACT! AVOID EXPOSURE OF (PREGNANT) WOMEN!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Cough. Headache. Sore throat. Weakness. Further see Ingestion.  Use closed system or ventilation.  Fresh air, rest. Refer for medical attention. 
Skin Redness. Pain.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection if powder.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Burning sensation. Diarrhoea. Vomiting. Shock or collapse.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: T, N; R: 45-23/25-50/53; S: 53-45-60-61; Note: A, E 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT5-II.  Store in an area without drain or sewer access. Well closed. Separated from acids and food and feedstuffs. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS CRYSTALS. 

Physical dangers
 

Chemical dangers
Upon heating, toxic fumes are formed. Reacts with acids. This produces toxic arsine gas (see ICSC 0222). Attacks many metals such as iron, aluminium and zinc in the presence of water. This produces toxic fumes of arsenic and arsine. 

Occupational exposure limits
TLV (as As): 0.01mg/m³ as TWA; A1 (confirmed human carcinogen); BEI issued; (ACGIH 2005).
MAK: Carcinogen category: 1; Germ cell mutagen group: 3A; (DFG 2005). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the cardiovascular system, central nervous system, gastrointestinal tract and kidneys. This may result in cardiac disorders, severe gastroenteritis, loss of fluids and electrolytes, kidney impairment, collapse and shock. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the peripheral nervous system, mucous membranes, skin, cardiovascular system, bone marrow, kidneys and liver. This may result in neuropathy, pigmentation disorders, perforation of the nasal septum, lesions of blood cells, kidney impairment and cirrhosis. This substance is carcinogenic to humans. Animal tests show that this substance possibly causes toxicity to human reproduction or development. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Decomposes at 180°C
Melting point: 130°C
Density: 1.9 g/cm³
Solubility in water, g/100ml at 21°C: 39  
This substance may be hazardous to the environment. Special attention should be given to ground water contamination, aquatic organisms and soil organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
The apparent melting point caused by loss of crystal water is given.
Depending on the degree of exposure, periodic medical examination is suggested.
Do NOT take working clothes home.
Card has been partially updated in January 2008: see Ingestion First Aid. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations