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METHYL METHACRYLATE
ICSC: 0300
Peer-Review Status: 26.11.2003 Validated
Methacrylic acid methyl ester
Methyl 2-methylpropenoate 
CAS #: 80-62-6 RTECS #: OZ5075000
UN #: 1247
EC #: 607-035-00-6
EINECS #: 201-297-1
    Formula: CH2C(CH3)COOCH3 / C5H8O2
Molecular mass: 100.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable.  NO open flames, NO sparks and NO smoking.  Use foam, powder, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT!   
Inhalation Cough. Shortness of breath. Sore throat.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Nausea. Vomiting. Abdominal pain.  Do not eat, drink, or smoke during work.  Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit and filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Remove all ignition sources. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.   
EC Classification
Symbol: F, Xi; R: 11-37/38-43; S: (2)-24-37-46; Note: D 
UN Classification
UN Hazard Class: 3; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30S1247.
NFPA Code: H2; F3; R2. 
Fireproof. Separated from strong oxidants, strong bases and strong acids. Cool. Keep in the dark. Keep in a well-ventilated room. Store only if stabilized. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour mixes well with air, explosive mixtures are easily formed. Vapours are uninhibited and may polymerize, causing blockage of vents. 

Chemical dangers
The substance may polymerize due to warming or due to heating, under the influence of light, polymerization catalysts and strong oxidants. This generates fire or explosion hazard. Reacts with strong acids and strong bases. 

Occupational exposure limits
TLV: 50 ppm as TWA; 100 ppm as STEL; (SEN); A4 (not classifiable as a human carcinogen); (ACGIH 2003).
MAK: 50 ppm, 210 mg/m³; Peak limitation category: I(2); Pregnancy risk group: C; Sensitization of skin (SH); (DFG 2003). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the peripheral nervous system. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 100.5°C
Melting point: -48°C
Relative density (water = 1): 0.94
Solubility in water, g/100ml at 20°C: 1.6
Vapour pressure, kPa at 20°C: 3.9
Relative vapour density (air = 1): 3.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.09
Flash point: 10°C o.c.
Auto-ignition temperature: 421°C
Explosive limits, vol% in air: 1.7-12.5
Octanol/water partition coefficient as log Pow: 1.38  
The substance is harmful to aquatic organisms. 

NOTES
Usually contains hydroquinone, hydroquinone methyl ether and dimethyl t-butylphenol as inhibitors of polymerization.
An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Methyl methacrylate (SIDS)
       Methyl methacrylate (CICADS 4, 1998)
       Methyl Methacrylate (IARC Summary & Evaluation, Volume 60, 1994)