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ISOPROPYL CHLOROFORMATE
ICSC: 0287
Peer-Review Status: 05.05.2003 Validated
Isopropyl chlorocarbonate
Chloroformic acid, isopropyl ester
Carbonochloridic acid 1-methylethyl ester
Isopropyl chloromethanate 
CAS #: 108-23-6 RTECS #: LQ6475000
UN #: 2407
EINECS #: 203-563-2
    Formula: C4H7ClO2 / (CH3)2CHOCOCl
Molecular mass: 122.6

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking.  Use carbon dioxide, dry powder, alcohol-resistant foam, dry sand. 
EXPLOSION Vapour/air mixtures are explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.  In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water. 
 
EXPOSURE   STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Burning sensation. Cough. Laboured breathing. Shortness of breath. Sore throat. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin Redness. Skin burns. Pain. Blisters.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Watering of the eyes. Redness. Pain. Severe deep burns.  Wear safety goggles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Burning sensation. Shock or collapse.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Ventilation. Remove all ignition sources. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
 
UN Classification
UN Hazard Class: 6.1; UN Subsidiary Risks: 3 and 8; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GTFC-I.  Fireproof. Separated from strong oxidants and food and feedstuffs. Dry. Well closed. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH PUNGENT ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including hydrogen chloride and phosgene. Reacts violently with strong oxidants. Reacts with water. This produces alcohol and hydrogen chloride (see ICSC 0163). 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C. 

Effects of short-term exposure
Lachrymation. The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the vapour may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 104.6°C
Relative density (water = 1): 1.08
Solubility in water: slow reaction
Vapour pressure, kPa at 20°C: 3
Relative vapour density (air = 1): 4.2
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.1
Flash point: 20°C c.c.
Auto-ignition temperature: >500°C
Explosive limits, vol% in air: 4-15 
 

NOTES
Health effects of exposure to the substance have not been investigated adequately.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
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    See Also:
       Toxicological Abbreviations