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CYCLOHEXIMIDE
ICSC: 0244
Peer-Review Status: 04.11.1997 Validated
4-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl) 2,6-piperidinedione
CAS #: 66-81-9 RTECS #: MA4375000
UN #: 2588
EC #: 613-140-00-8
EINECS #: 200-636-0
    Formula: C15H23NO4
Molecular mass: 281.35

TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE Gives off irritating or toxic fumes (or gases) in a fire.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION      
 
EXPOSURE   PREVENT DISPERSION OF DUST! STRICT HYGIENE!   
Inhalation   Use local exhaust or breathing protection.  Fresh air, rest. 
Skin Redness. Pain.  Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety spectacles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Diarrhoea. Unconsciousness. See Notes.  Do not eat, drink, or smoke during work.  Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT wash away into sewer. Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: T+, N; R: 61-28-51/53-68; S: 53-45-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT7-I.  Separated from food and feedstuffs. Well closed. Keep in a well-ventilated room. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS CRYSTALS. 

Physical dangers
 

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including nitrogen oxides. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly. 

Effects of short-term exposure
The substance is irritating to the eyes and skin. Exposure could cause death. See Notes. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Melting point: 119.5-121°C
Solubility in water, g/100ml at 2°C: 2.1
Octanol/water partition coefficient as log Pow: 0.55  
This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.
Animal studies have indicated that the substance may be very toxic by ingestion.
Hizarocin, Acti-dione, Acti-aid, Naramycin, Naramycin A and Neocycloheximide are trade names.
Card has been partly updated in October 2005.
See sections EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations