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CHLORAL HYDRATE
ICSC: 0234
Peer-Review Status: 12.04.2013 Validated
Trichloroacetaldehyde monohydrate
2,2,2-Trichloro-1,1-ethanediol 
CAS #: 302-17-0 RTECS #: FM8750000
UN #: 2811
EC #: 605-014-00-6
EINECS #: 206-117-5
    Formula: C2H3Cl3O2 / Cl3CCH(OH)2
Molecular mass: 165.4

TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION     In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   PREVENT DISPERSION OF DUST!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Cough. Confusion. Drowsiness. Nausea. Unconciousness.  Use local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer immediately for medical attention. 
Skin Redness.  Protective gloves.  Rinse skin with plenty of water or shower. 
Eyes Redness.  Wear safety spectacles or eye protection in combination with breathing protection if powder.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Vomiting. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T; R: 25-36/38; S: (1/2)-25-45 
UN Classification
UN Hazard Class: 6.1 
GHS Classification
Signal: Danger
Toxic if swallowed
Causes skin irritation
Causes serious eye irritation
Suspected of causing genetic defects
May cause cancer
May cause drowsiness or dizziness 
skull;toxiccancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
  Separated from strong bases and food and feedstuffs. 

IMPORTANT DATA
Physical State; Appearance
TRANSPARENT COLOURLESS CRYSTALS WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including hydrogen chloride. Reacts with strong bases. This produces chloroform. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour or dust and by ingestion. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. This may result in disorientation, lowering of blood pressure and lowering of consciousness. Exposure at high levels could cause cardiac dysrhythmia and unconsciousness or death. 

Effects of long-term or repeated exposure
The substance may have effects on the liver. This may result in addiction, behavioural effects and liver impairment. This substance is probably carcinogenic to humans. May cause heritable genetic damage to human germ cells. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Decomposes at 97°C
Melting point: 57-60°C
Density: 1.9 g/cm³
Solubility in water: very good
Octanol/water partition coefficient as log Pow: 0.99  
This substance may be hazardous to the environment. Special attention should be given to aquatic organisms. 

NOTES
Use of alcoholic beverages enhances the harmful effect.
Depending on the degree of exposure, periodic medical examination is suggested. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Chloral hydrate (CICADS 25, 2000)