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2-AMINOPYRIDINE
ICSC: 0214
Peer-Review Status: 22.04.2004 Validated
o-Aminopyridine
alpha-Aminopyridine 
CAS #: 504-29-0 RTECS #: US1575000
UN #: 2671
EINECS #: 207-988-4
    Formula: C5H6N2 / NH2C5H4N
Molecular mass: 94.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Finely dispersed particles form explosive mixtures in air.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent deposition of dust.   
 
EXPOSURE   STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Convulsions. Dizziness. Headache. Nausea. Shortness of breath. Weakness.  Use local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations.  Airtight.
Do not transport with food and feedstuffs. 
EC Classification
 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT2-II.  Separated from food and feedstuffs, strong oxidants and strong acids. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS OR WHITE POWDER OR CRYSTALS WITH CHARACTERISTIC ODOUR. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. 

Chemical dangers
Decomposes on burning. This produces nitrogen oxides. Reacts with strong oxidants. This generates fire and explosion hazard. The solution in water is a strong base. It reacts violently with acid and is corrosive. 

Occupational exposure limits
TLV: 0.5ppm as TWA; (ACGIH 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes and skin. The substance may cause effects on the central nervous system. This may result in convulsions and respiratory depression. Exposure could cause an increase in blood pressure. Exposure far above the OEL could cause death. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 211°C
Melting point: 58°C
Solubility in water: very good
Vapour pressure, kPa at 25°C: 0.8
Relative vapour density (air = 1): 3.2
Flash point: 68°C c.c.
Octanol/water partition coefficient as log Pow: 0.49  
The substance is toxic to aquatic organisms. 

NOTES
There is no odour warning even when toxic concentrations are present.
The relation between odour and the occupational exposure limit cannot be indicated.
Card has been partly updated in October 2005.
See section Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations