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STRYCHNINE
ICSC: 0197
Peer-Review Status: 04.12.2000 Validated
Strychnidin-10-one 
CAS #: 57-24-9 RTECS #: WL2275000
UN #: 1692
EC #: 614-003-00-5
EINECS #: 200-319-7
    Formula: C21H22N2O2
Molecular mass: 334.4

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO contact with oxidizing agents.  In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION      
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation See Ingestion.  Use local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin   Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes   Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Convulsions. Muscle stiffness. Shock or collapse.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer for medical attention . Avoid unnecessary stimulation of the victim. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: T+, N; R: 27/28-50/53; S: (1/2)-36/37-45-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT2-I.  Provision to contain effluent from fire extinguishing. Separated from strong oxidants and food and feedstuffs. Well closed. 

IMPORTANT DATA
Physical State; Appearance
ODOURLESS AND COLOURLESS CRYSTALS WITH BITTER TASTE. 

Physical dangers
 

Chemical dangers
Decomposes on heating. This produces toxic fumes including nitrogen oxides. The substance is a weak base. Reacts with strong oxidants. This generates fire and explosion hazard. 

Occupational exposure limits
TLV: 0.15mg/m³ as TWA; (ACGIH 2004).
MAK (2b (not established but data is available)): (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. 

Effects of short-term exposure
The substance may cause effects on the central nervous system. This may result in convulsions, muscle contractions and respiratory failure. Exposure could cause death. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Decomposes
Melting point: 275-285°C
Density: 1.36 g/cm³
Solubility in water: none
Octanol/water partition coefficient as log Pow: 1.68  
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to birds. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Card has been partly updated in April 2005.
See sections Occupational Exposure Limits, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Strychnine (PIM 507)