IPCS INCHEM Home
PROPOXUR
ICSC: 0191
Peer-Review Status: 27.10.1994 Validated
2-Isopropoxyphenyl methylcarbamate
Phenol, 2-(1-methylethoxy)-,methylcarbamate
2-(1-Methylethoxy)phenyl methylcarbamate
PHC 
CAS #: 114-26-1 RTECS #: FC3150000
UN #: 2757
EC #: 006-016-00-4
EINECS #: 204-043-8
    Formula: C11H15NO3
Molecular mass: 209.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible under specific conditions. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, foam, powder, carbon dioxide. 
EXPLOSION      
 
EXPOSURE   PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Dizziness. Headache. Sweating. Laboured breathing. Nausea. Unconciousness. Vomiting. Pupillary constriction, muscle cramp, excessive salivation.  Use local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Refer for medical attention. See Notes. 
Skin MAY BE ABSORBED! Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Pupillary constriction. Blurred vision.  Wear safety spectacles or eye protection in combination with breathing protection if powder.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal cramps. Convulsions. Diarrhoea. Weakness. Muscle twitching. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention . See Notes. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT wash away into sewer. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: T, N; R: 25-50/53; S: (1/2)-37-45-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT7-III.  Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room. 

IMPORTANT DATA
Physical State; Appearance
WHITE CRYSTALLINE POWDER. 

Physical dangers
 

Chemical dangers
Decomposes on heating and on burning. This produces toxic fumes including methyl isocyanate and nitrogen oxides. 

Occupational exposure limits
TLV: 0.5mg/m³ as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued; (ACGIH 2004).
MAK (inhalable fraction): 2 mg/m³; Peak limitation category: II(8); (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. 

Effects of short-term exposure
The substance may cause effects on the nervous system, liver and kidneys. This may result in respiratory failure, convulsions and tissue lesions. Cholinesterase inhibition. Exposure could cause death. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Melting point: 91°C
Solubility in water, g/100ml at 20°C: 0.2 (poor)
Vapour pressure, Pa at 20°C: 0.001
Octanol/water partition coefficient as log Pow: 1.52  
This substance may be hazardous to the environment. Special attention should be given to mammals, birds, aquatic organisms, soil organisms and bees. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
If the substance is formulated with solvents also consult the ICSCs of these materials.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Baygon, Blattanex, Bolfo, Invisi-Gard, Isocarb, o-IMPC, Propyon, Rhoden, Sendran, Suncide, Tendex, Tugon Fliegenkugel, Unden, Undene are trade names.
If the substance is present under the form of a formulation containing hydrocarbon solvents, vomiting may not be induced.
Card has been partly updated in October 2005.
See sections Occupational Exposure Limits, EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Propoxur (WHO Pesticide Residues Series 3)
       Propoxur (Pesticide residues in food: 1981 evaluations)
       Propoxur (Pesticide residues in food: 1983 evaluations)
       Propoxur (Pesticide residues in food: 1989 evaluations Part II Toxicology)