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CHLOROTHALONIL
ICSC: 0134
Peer-Review Status: 26.11.2009 Validated
Tetrachloroisophthalonitrile
2,4,5,6-Tetrachloro-1,3-benzenedicarbonitrile
2,4,5,6-Tetrachloro-3-cyanobenzonitrile 
CAS #: 1897-45-6 RTECS #: NT2600000
UN #: 2588
EC #: 608-014-00-4
EINECS #: 217-588-1
    Formula: C8Cl4N2
Molecular mass: 265.9

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.    Use water spray, foam, powder, carbon dioxide. 
EXPLOSION Risk of fire and explosion if formulations contain flammable/explosive solvents.     
 
EXPOSURE   AVOID ALL CONTACT!   
Inhalation   Use local exhaust or breathing protection.  Fresh air, rest. 
Skin Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision.  Wear safety spectacles or eye protection in combination with breathing protection if powder.  Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention. 
Ingestion Burning sensation in the throat and chest. Abdominal pain.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit and protective gloves. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: T+, N; R: 26-37-40-41-43-50/53; S: (2)-28-36/37/39-45-60-61 
UN Classification
UN Hazard Class: 6.1 
GHS Classification
Signal: Danger
Fatal if inhaled dust
Causes mild skin irritation
Causes serious eye irritation
May cause an allergic skin reaction
May cause respiratory irritation
Very toxic to aquatic life 
skull;toxicenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
  Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
ODOURLESS COLOURLESS CRYSTALS. 

Physical dangers
No data. 

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including hydrogen chloride (see ICSC 0163) and nitrogen oxides. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK: Carcinogen category: 3B; Sensitization of skin (SH); (DFG 2009). 

Routes of exposure
The substance can be absorbed into the body by inhalation. 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed. 

Effects of short-term exposure
The substance is severely irritating to the eyes. The substance is irritating to the respiratory tract. The substance is mildly irritating to the skin. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 350°C
Melting point: 250-251°C
Relative density (water = 1): 1.8
Solubility in water, g/100ml at 25°C: <0.01 (none)
Vapour pressure, Pa at 40°C: <1.3 (negligible)
Octanol/water partition coefficient as log Pow: 3.05  
The substance is very toxic to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Carrier solvents used in commercial formulations may change physical and toxicological properties. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Chlorothalonil (EHC 183, 1996)
       Chlorothalonil (HSG 98, 1995)
       Chlorothalonil (WHO Pesticide Residues Series 4)
       Chlorothalonil (Pesticide residues in food: 1977 evaluations)
       Chlorothalonil (Pesticide residues in food: 1981 evaluations)
       Chlorothalonil (Pesticide residues in food: 1983 evaluations)
       Chlorothalonil (Pesticide residues in food: 1985 evaluations Part II Toxicology)
       Chlorothalonil (Pesticide residues in food: 1987 evaluations Part II Toxicology)
       Chlorothalonil (Pesticide residues in food: 1990 evaluations Toxicology)
       Chlorothalonil (Pesticide residues in food: 1992 evaluations Part II Toxicology)
       Chlorothalonil  (IARC Summary & Evaluation, Volume 30, 1983)
       Chlorothalonil  (IARC Summary & Evaluation, Volume 73, 1999)