VOL.: 30 (1983) (p. 329)
Chem. Abstr. Name: (1,1'-Biphenyl)-2-ol
Chem. Abstr. Name: (1,1'-Biphenyl)-2-ol, sodium salt
The available data were insufficient to evaluate the teratogenicity of sodium ortho-phenylphenate to experimental animals.
ortho-Phenylphenol and sodium ortho-phenylphenate have been subjected to a variety of mutagenicity tests, including those using rodents, without demonstrating any unambiguous mutagenic or DNA damaging effect. Commercial preparations have been reported to contain uncharacterized impurities capable of inducing chromosomal aberrations in cultured mammalian cells.
No data were available to evaluate the teratogenic or chromosomal effects of ortho-phenylphenol or sodium ortho-phenylphenate in humans.
No case report or epidemiological study of the carcinogenicity of ortho-phenylphenol or sodium ortho-phenylphenate alone was available to the Working Group. (See also the section 'Cancer Epidemiology of Pesticide Manufacturers, Formulators and Users', in this volume.)
The available data are insufficient to evaluate the carcinogenicity of ortho-phenylphenol or sodium ortho-phenylphenate to humans.
For definition of the italicized terms, see Preamble Evaluation.
Subsequent evaluations: Suppl. 7 (1987) (p. 70: ortho-phenylphenol - Group 3; p. 392: sodium ortho-phenylphenate - Group 2B); Vol. 73 (1999)
See Also: Toxicological Abbreviations Phenylphenol, ortho- and its Sodium Salt (IARC Summary & Evaluation, Volume 73, 1999)