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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

HEXACHLOROETHANE

VOL.: 20 (1979) (p. 467)

CAS No.: 67-72-1

5. Summary of Data Reported and Evaluation

5.1 Experimental data

Hexachloroethane was tested in one experiment in mice and in one in rats by oral administration. In mice, it produced malignant liver tumours in males and females. In rats, no statistically significant excess of tumours was observed; however, a few renal tumours, rarely seen in untreated animals, were found.

5.2 Human data

No case reports or epidemiological studies were available to the Working Group.

The production and many uses of hexachloroethane for over 50 years, and its occurrence in water and air, indicate that human exposure occurs.

5.3 Evaluation

There is limited evidence that hexachloroethane is carcinogenic in experimental animals.

Subsequent evaluations: Suppl. 7 (1987) (p. 64); Vol. 73 (1999)

For definition of terms, see Preamble Evaluation.

Synonyms


Last updated: 30 September 1999






















    See Also:
       Toxicological Abbreviations
       Hexachloroethane (ICSC)
       Hexachloroethane  (IARC Summary & Evaluation, Volume 73, 1999)