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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

DITHRANOL

VOL.: 13 (1977) (p. 75)

CAS No.: 1148-38-0
Chem. Abstr. Name: 1,8,9-Anthracenetriol

5. Summary of Data Reported and Evaluation

5.1 Animal data

Dithranol is a tumour-promoting agent in mouse skin carcinogenesis experiments following initiation with either 7,12-dimethylbenz[a]anthracene or urethane. An increased incidence of lymphomas was also observed in mice painted with dithranol after urethane initiation.

5.2 Human data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 63: Group 3)

For definition of Groups, see Preamble Evaluation.

Synonyms


Last updated: 25 March 1998






















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