International Agency for Research on Cancer (IARC) - Summaries & Evaluations
DIALLATE
VOL.: 12 (1976) (p. 69)
CAS No.: 2303-16-4
Chem. Abstr. Name: Bis(l-methylethyl) carbamothioic acid, S-(2,3-dichloro-2-propenyl)ester
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
Diallate is carcinogenic in mice after its oral administration: it
produced an increased incidence of liver-cell tumours in males of two
strains and a slight increase in the number of liver-cell tumours in
females of one strain. A single subcutaneous injection in mice
produced a slight increase in the incidence of systemic reticulum-cell
sarcomas in males of one strain.
5.2 Human carcinogenicity data
No case reports or epidemiological studies were available to the
Working Group.
Subsequent evaluation: Vol. 30 (1983);
Suppl. 7 (1987) (p. 61: Group 3)
For definition of Groups, see Preamble Evaluation.
Last updated: 25 March 1998