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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

MONOCROTALINE

VOL.: 10 (1976) (p. 291)

CAS No.: 315-22-0

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Monocrotaline is carcinogenic in rats following its oral administration, the only species and route of administration tested; it produced carcinomas of the liver (see also the section "General Information and Conclusions on Pyrrolizidine Alkaloids", in this volume).

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 67: Group 2B)

For definition of Groups, see Preamble Evaluation.

Synonyms


Last updated: 22 March 1998






















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