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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

OESTRADIOL MUSTARD

VOL.: 9 (1975) (p. 217)

CAS No.: 22966-79-6
Chem. Abstr. Name: Estra-1,3,5(10)-triene-3,17b-diol,bis({para-[bis-(2-chloroethyl)-
amino]phenyl}acetate)

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Oestradiol mustard is carcinogenic in mice following its intraperitoneal injection, the only species and route tested, producing a dose-related increase in the incidence of lung tumours.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (p. 68: Group 3)

For definition of Groups, see Preamble Evaluation.

Synonyms


Last updated: 21 March 1998






















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