International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 9 (1975) (p. 95)

CAS No.: 51-18-3
Chem. Abstr. Name: 2,4,6-Tris(1-aziridinyl)-1,3,5-triazine

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

2,4,6-Tris(l-aziridinyl)-s-triazine is carcinogenic in mice following its intraperitoneal injection, producing an increase in the incidence of ovarian, thymic and lung tumours. It also acted as an initiator of skin carcinogenesis. In rats it produced sarcomas at the site of its subcutaneous injection.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 73: Group 3)

For definition of Groups, see Preamble Evaluation.


Last updated: 21 March 1998

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