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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

CITRUS RED No. 2

VOL.: 8 (1975) (p. 101)

CAS No.: 6358-53-8
Chem. Abstr. Name: 1-[(2,5-Dimethoxyphenyl)azo]-2-naphthalenol

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Citrus red No. 2 is carcinogenic in mice and rats. Following its oral administration it produced hyperplasia and tumours of the bladder. Given subcutaneously, it produced adenocarcinomas of the lung and lymphosarcomas in female mice. Its administration in mice by bladder implantation produced carcinomas of that organ.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 60: Group 2B)

For definition of Groups, see Preamble Evaluation.

Synonyms


Last updated: 23 March 1998






















    See Also:
       Toxicological Abbreviations
       CITRUS RED No. 2 (JECFA Evaluation)