3,3'-Dichlorobenzidine (IARC Summary & Evaluation, Volume 4, 1974)

International Agency for Research on Cancer (IARC) - Summaries & Evaluations

3,3'-DICHLOROBENZIDINE

VOL.: 4 (1974) (p. 49)

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

3,3'-Dichlorobenzidine is carcinogenic in the rat following oral and subcutaneous administration and in the hamster after oral administration.

5.2 Human carcinogenicity data

No epidemiological data are available, but as 3,3'-dichlorobenzidine and benzidine may be made in the same plant, the possibility cannot be excluded that 3,3'-dichlorobenzidine has contributed to the incidence of bladder cancer attributed to benzidine.

Subsequent evaluations: Vol. 29 (1982); Suppl. 7 (1987)

Last updated: 16 March 1998





























    See Also:
       Toxicological Abbreviations
       Dichlorobenzidine, 3,3'-  (IARC Summary & Evaluation, Supplement7, 1987)