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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

DIBENZO(a,h)PYRENE

VOL.: 3 (1973) (p. 207)

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Carcinogenic effects of dibenzo(a,h)pyrene were demonstrated following repeated skin painting in mice and injections in mice and rats. In the skin painting experiment, it was less active than benzo(a)pyrene. It has not been tested by other routes or in other species.

5.2 Human carcinogenicity data

No case reports or epidemiological studies on the significance of dibenzo(a,h)pyrene exposure to man are available. However, coal-tar and other materials which are known to be carcinogenic to man may contain dibenzo(a,h)pyrene. The substance has also been detected in other environmental situations. The possible contribution of polycyclic aromatic hydrocarbons from some environmental sources to the overall carcinogenic risk to man is discussed in the General Remarks.

Subsequent evaluations: Vol. 32 (1983); Suppl. 7 (1987) (p. 62: Group 2B)

For definition of Groups, see Preamble Evaluation.


Last updated: 16 March 1998






















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