International Agency for Research on Cancer (IARC) - Summaries & Evaluations
DIBENZO(a,e)PYRENE
VOL.: 3 (1973) (p. 201)
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
Dibenzo(a,e)pyrene has produced tumours in mice following skin paintings and
s.c. injection. In skin painting experiments, dibenzo(a,e)pyrene was less
active than benzo(a)pyrene. It has not been tested by other routes in
the mouse or in other species.
5.2 Human carcinogenicity data
No case reports or epidemiological studies on the significance of
dibenzo(a,e)pyrene exposure to man are available. The only reported occurrence
of this substance was in the exhaust of internal combustion engines.
Subsequent evaluations: Vol. 32 (1983); Suppl. 7 (1987) (p. 62: Group 2B)
For definition of Groups, see Preamble Evaluation.
Last updated: 16 March 1998